• WHERE: State Farm Stadium (Glendale, Ariz.)
• WHEN: 8:15 p.m. ET | ESPN
• SPREAD: Cardinals -2.5 | O/U: 51.5

In general, I’m wary of the 2.5-point home favorite, the type of team that Vegas is almost begging the public to take. That’s where this line is at publishing despite Arizona’s superior résumé and complete profile, including improved health. There is a certain logic to the Rams, a mostly veteran team, rounding into form this week. It’s hard to sweep a division rival, and Los Angeles has the talent to put it all together down the stretch. Still, winning this game would take the best effort from Sean McVay’s crew since the Week 3 win over Tampa. For the Cardinals, their average game should be good enough.